PDGF receptor-β modulates metanephric mesenchyme chemotaxis induced by PDGF AA

PDGF B chain or PDGF receptor (PDGFR)-β-deficient (−/−) mice lack mesangial cells. To study responses of α- and β-receptor activation to PDGF ligands, metanephric mesenchymal cells (MMCs) were established from embryonic day E11.5 wild-type (+/+) and −/− mouse embryos. PDGF BB stimulated cell migrati...

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Hlavní autoři: Ricono, Jill M., Wagner, Brent, Gorin, Yves, Arar, Mazen, Kazlauskas, Andrius, Choudhury, Goutam Ghosh, Abboud, Hanna E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643859/
https://ncbi.nlm.nih.gov/pubmed/19019919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90368.2008
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