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Spliceosome Assembly Pathways for Different Types of Alternative Splicing Converge during Commitment to Splice Site Pairing in the A Complex

Differential splice site pairing establishes alternative splicing patterns resulting in the generation of multiple mRNA isoforms. This process is carried out by the spliceosome, which is activated by a series of sequential structural rearrangements of its five core snRNPs. To determine when splice s...

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Hlavní autoři: Kotlajich, Matthew V., Crabb, Tara L., Hertel, Klemens J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643811/
https://ncbi.nlm.nih.gov/pubmed/19064642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01071-08
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