Deficiency of the Tetraspanin CD63 Associated with Kidney Pathology but Normal Lysosomal Function

CD63 is a member of the tetraspanin superfamily that constitutes a main component of the lysosomal membrane. In mice, two CD63 gene loci are present, with only one of these two being functional. We generated and analyzed mice deficient for active CD63. Disruption of CD63 results in a complete loss o...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Schröder, Jenny, Lüllmann-Rauch, Renate, Himmerkus, Nina, Pleines, Irina, Nieswandt, Bernhard, Orinska, Zane, Koch-Nolte, Friedrich, Schröder, Bernd, Bleich, Markus, Saftig, Paul
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
Предметы:
Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643809/
https://ncbi.nlm.nih.gov/pubmed/19075008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01163-08
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы