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Deficiency of the Tetraspanin CD63 Associated with Kidney Pathology but Normal Lysosomal Function
CD63 is a member of the tetraspanin superfamily that constitutes a main component of the lysosomal membrane. In mice, two CD63 gene loci are present, with only one of these two being functional. We generated and analyzed mice deficient for active CD63. Disruption of CD63 results in a complete loss o...
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| Hoofdauteurs: | , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology (ASM)
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2643809/ https://ncbi.nlm.nih.gov/pubmed/19075008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01163-08 |
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