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The tetraspanin CD63 is required for efficient IgE-mediated mast cell degranulation and anaphylaxis
Mast cell activation through the high affinity IgE receptor FcεRI leads to the release of mediators involved in immediate-type allergic reactions. While antibodies against the tetraspanins CD63 and CD81 inhibit FcεRI-induced mast cell degranulation, the intrinsic role of these molecules in FcεRI-ind...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3780990/ https://ncbi.nlm.nih.gov/pubmed/23945142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202323 |
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