Live Attenuated Influenza Viruses Containing NS1 Truncations as Vaccine Candidates against H5N1 Highly Pathogenic Avian Influenza

Due to the high mortality associated with recent, widely circulating strains of H5N1 influenza virus in poultry, the recurring introduction of H5N1 viruses from birds to humans, and the difficulties in H5N1 eradication by elimination of affected flocks, an effective vaccine against HPAI (highly path...

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Main Authors: Steel, John, Lowen, Anice C., Pena, Lindomar, Angel, Matthew, Solórzano, Alicia, Albrecht, Randy, Perez, Daniel R., García-Sastre, Adolfo, Palese, Peter
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643794/
https://ncbi.nlm.nih.gov/pubmed/19073731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01920-08
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