Tight Junction Proteins Claudin-1 and Occludin Control Hepatitis C Virus Entry and Are Downregulated during Infection To Prevent Superinfection

A tight junction (TJ) protein, claudin-1 (CLDN1), was identified recently as a key factor for hepatitis C virus (HCV) entry. Here, we show that another TJ protein, occludin, is also required for HCV entry. Mutational study of CLDN1 revealed that its tight junctional distribution plays an important r...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Shufeng, Yang, Wei, Shen, Le, Turner, Jerrold R., Coyne, Carolyn B., Wang, Tianyi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Virus-Cell Interactions
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643775/
https://ncbi.nlm.nih.gov/pubmed/19052094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01888-08
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