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Lower Levels of Gamma Interferon Expressed by a Pseudotyped Single-Cycle Simian Immunodeficiency Virus Enhance Immunogenicity in Rats

A vaccine for human immunodeficiency virus (HIV) infection is desperately needed to control the AIDS pandemic. To address this problem, we constructed single-cycle simian immunodeficiency viruses (SIVs) pseudotyped with the glycoprotein of vesicular stomatitis virus and expressing different levels o...

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Detalhes bibliográficos
Main Authors: Peng, Yue, Lin, Fan-ching, Verardi, Paulo H., Jones, Leslie A., Yilma, Tilahun D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643767/
https://ncbi.nlm.nih.gov/pubmed/19073726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01446-08
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