High-Resolution Functional Profiling of a Gammaherpesvirus RTA Locus in the Context of the Viral Genome

Gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus are associated with multiple human cancers. Our goal was to develop a quantitative, high-throughput functional profiling system to identify viral cis-elements and protein subdomains critical for virus replication...

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Autores principales: Arumugaswami, Vaithilingaraja, Sitapara, Ronika, Hwang, Seungmin, Song, Moon Jung, Ho, Tuyet Ngoc, Su, Nancy Qi, Sue, Eric Y., Kanagavel, Vidhya, Xing, Fangfang, Zhang, Xiaolin, Zhao, Minglei, Deng, Hongyu, Wu, Ting-Ting, Kanagavel, Sudhakar, Zhang, LuLu, Dandekar, Sugandha, Papp, Jeanette, Sun, Ren
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643748/
https://ncbi.nlm.nih.gov/pubmed/19073723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02302-08
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