Anthrax Lethal Toxin Triggers the Formation of a Membrane-Associated Inflammasome Complex in Murine Macrophages

Multiple microbial components trigger the formation of an inflammasome complex that contains pathogen-specific nucleotide oligomerization and binding domain (NOD)-like receptors (NLRs), caspase-1, and in some cases the scaffolding protein ASC. The NLR protein Nalp1b has been linked to anthrax lethal...

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Detalhes bibliográficos
Main Authors: Nour, Adel M., Yeung, Yee-Guide, Santambrogio, Laura, Boyden, Eric D., Stanley, E. Richard, Brojatsch, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643637/
https://ncbi.nlm.nih.gov/pubmed/19124602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01032-08
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