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Mitochondrial DNA Damage in Iron Overload

Chronic iron overload has slow and insidious effects on heart, liver, and other organs. Because iron-driven oxidation of most biologic materials (such as lipids and proteins) is readily repaired, this slow progression of organ damage implies some kind of biological “memory.” We hypothesized that cum...

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Autori principali: Gao, Xueshan, Campian, Jian Li, Qian, Mingwei, Sun, Xiao-Feng, Eaton, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643512/
https://ncbi.nlm.nih.gov/pubmed/19095657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806235200
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