The Endoplasmic Reticulum Enzyme DGAT2 Is Found in Mitochondria-associated Membranes and Has a Mitochondrial Targeting Signal That Promotes Its Association with Mitochondria

The synthesis and storage of neutral lipids in lipid droplets is a fundamental property of eukaryotic cells, but the spatial organization of this process is poorly understood. Here we examined the intracellular localization of acyl-CoA:diacylglycerol acyltransferase 2 (DGAT2), an enzyme that catalyz...

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Bibliographic Details
Main Authors: Stone, Scot J., Levin, Malin C., Zhou, Ping, Han, Jiayi, Walther, Tobias C., Farese, Robert V.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643492/
https://ncbi.nlm.nih.gov/pubmed/19049983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805768200
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