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Efficient Gene Delivery Vectors by Tuning the Surface Charge Density of Amino Acid-Functionalized Gold Nanoparticles

Gold colloids functionalized with amino acids provide a scaffold for effective DNA binding with subsequent condensation. Particles with lysine and lysine dendron functionality formed particularly compact complexes and provided highly efficient gene delivery without any observed cytotoxicity. Nanopar...

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Bibliografische gegevens
Hoofdauteurs: Ghosh, Partha S., Kim, Chae-Kyu, Han, Gang, Forbes, Neil S., Rotello, Vincent M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643365/
https://ncbi.nlm.nih.gov/pubmed/19206385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn800507t
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