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Polyethylene glycol, unique among laxatives, suppresses aberrant crypt foci, by elimination of cells

BACKGROUND: Polyethylene glycol (PEG), an osmotic laxative, is a very potent inhibitor of colon cancer in rats. In a search for mechanisms, we tested the hypothesis that fecal bulking and moisture decreases colon carcinogenesis. We also looked for PEG effects on crypt cells in vivo. METHODS: Fischer...

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Autori principali: Taché, Sylviane, Parnaud, Géraldine, Van Beek, Erik, Corpet, Denis E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643349/
https://ncbi.nlm.nih.gov/pubmed/16716974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00365520500380668
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