Toll-like Receptor 2 Is Essential for the Sensing of Oxidants during Inflammation

Rationale: The mechanisms by which oxidants are sensed by cells and cause inflammation are not well understood. Objectives: This study aimed to determine how cells “sense” soluble oxidants and how this is translated into an inflammatory reaction. Methods: Monocytes, macrophages, or HEK293 cells (sta...

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Hlavní autoři: Paul-Clark, Mark J., McMaster, Shaun K., Sorrentino, Rosalinda, Sriskandan, Shiranee, Bailey, Lucy K., Moreno, Laura, Ryffel, Bernhard, Quesniaux, Valerie F., Mitchell, Jane A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2009
Témata:
C. Critical Care
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643079/
https://ncbi.nlm.nih.gov/pubmed/19011150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200707-1019OC
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