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Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1

In the pituitary, the transition from proliferating progenitor cell into differentiated hormone producing cell is carefully regulated in a time dependent and spatially restricted manner. We report that two targets of Notch signaling, Hes1 and Prop1, are needed to maintain progenitors within Rathke’s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Himes, Ashley D., Raetzman, Lori T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642967/
https://ncbi.nlm.nih.gov/pubmed/18996108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.10.010
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