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Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1

In the pituitary, the transition from proliferating progenitor cell into differentiated hormone producing cell is carefully regulated in a time dependent and spatially restricted manner. We report that two targets of Notch signaling, Hes1 and Prop1, are needed to maintain progenitors within Rathke’s...

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Autori principali: Himes, Ashley D., Raetzman, Lori T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642967/
https://ncbi.nlm.nih.gov/pubmed/18996108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.10.010
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