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Expression and localization of GPR109A (PUMA-G/HM74A) mRNA and protein in mammalian retinal pigment epithelium

PURPOSE: GPR109A has been identified as a G-protein-coupled receptor for niacin. β-hydroxybutyrate (β-HB) is a physiologic ligand for the receptor. β-HB, the predominate ketone body in circulation, is an important energy source for neurons, including retinal neurons, under various physiologic and pa...

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Auteurs principaux: Martin, Pamela M., Ananth, Sudha, Cresci, Gail, Roon, Penny, Smith, Sylvia, Ganapathy, Vadivel
Format: Artigo
Langue:Inglês
Publié: Molecular Vision 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642846/
https://ncbi.nlm.nih.gov/pubmed/19223991
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