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Mismatch oligonucleotides in human and yeast: guidelines for probe design on tiling microarrays

BACKGROUND: Mismatched oligonucleotides are widely used on microarrays to differentiate specific from nonspecific hybridization. While many experiments rely on such oligos, the hybridization behavior of various degrees of mismatch (MM) structure has not been extensively studied. Here, we present the...

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Autors principals: Seringhaus, Michael, Rozowsky, Joel, Royce, Thomas, Nagalakshmi, Ugrappa, Jee, Justin, Snyder, Michael, Gerstein, Mark
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642824/
https://ncbi.nlm.nih.gov/pubmed/19117516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-635
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