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Unexpected Orthogonality of S-Benzoxazolyl and S-Thiazolinyl Glycosides: Application to Expeditious Oligosaccharide Assembly

[Image: see text] Thorough mechanistic studies of the alkylation pathway for the activation of glycosyl thioimidates have led to the development of the “thioimidate-only orthogonal strategy”. Discrimination amongst S-thiazolinyl (STaz) and S-benzoxazolyl (SBox) anomeric leaving group was achieved by...

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Autori principali: Kaeothip, Sophon, Pornsuriyasak, Papapida, Rath, Nigam P., Demchenko, Alexei V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642804/
https://ncbi.nlm.nih.gov/pubmed/19161321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol802740b
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