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Oxidant regulated inter-subunit disulfide bond formation between ASIC1a subunits
The acid-sensing ion channel-1a (ASIC1a) is composed of 3 subunits and is activated by a decrease in extracellular pH. It plays an important role in diseases associated with a reduced pH and production of oxidants. Previous work showed that oxidants reduce ASIC1a currents. However, the effects on ch...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2642663/ https://ncbi.nlm.nih.gov/pubmed/19218436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813402106 |
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