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Retinoic acid dependent regulation of immune responses by dendritic cells and macrophages

Dendritic cells (DCs) control the strength and quality of antigen-specific T and B cell responses. Recent advances point to a novel mechanism, in which metabolism of vitamin A into retinoic acid (RA) in DCs, regulate critical parameters of lymphocyte differentiation. First, RA enhances the induction...

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Bibliographic Details
Main Authors: Manicassamy, Santhakumar, Pulendran, Bali
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642591/
https://ncbi.nlm.nih.gov/pubmed/18778953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2008.07.007
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