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Functional specializations of intestinal dendritic cell and macrophage subsets that control T(H)-17 and T regulatory responses is dependent on the T:APC ratio, source of mouse strain and regional localization

Although several subsets of intestinal antigen presenting cells (APCs) have been described, to date is no systematic evaluation of their phenotypes, functions and geographical localization. Here we used 10-color flow cytometry, to define the major APC subsets in the small and large intestine LP. LP...

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Detalhes bibliográficos
Main Authors: Denning, Timothy L, Norris, Brian A, Medina-Contreras, Oscar, Manicassamy, Santhakumar, Geem, Duke, Madan, Rajat, Karp, Christopher L, Pulendran, Bali
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131424/
https://ncbi.nlm.nih.gov/pubmed/21666057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002701
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