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Nonsense Codons Trigger an RNA Partitioning Shift
T-cell receptor-β (TCRβ) genes naturally acquire premature termination codons (PTCs) as a result of programmed gene rearrangements. PTC-bearing TCRβ transcripts are dramatically down-regulated to protect T-cells from the deleterious effects of the truncated proteins that would otherwise be produced....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2640978/ https://ncbi.nlm.nih.gov/pubmed/19091751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805193200 |
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