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The N-terminal Amphipathic α-Helix of Viperin Mediates Localization to the Cytosolic Face of the Endoplasmic Reticulum and Inhibits Protein Secretion

Viperin is an evolutionarily conserved interferon-inducible protein that localizes to the endoplasmic reticulum (ER) and inhibits a number of DNA and RNA viruses. In this study, we report that viperin specifically localizes to the cytoplasmic face of the ER and that an amphipathic α-helix at its N t...

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Bibliografske podrobnosti
Main Authors: Hinson, Ella R., Cresswell, Peter
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640954/
https://ncbi.nlm.nih.gov/pubmed/19074433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807261200
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