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Use of chromosome substitution strains to identify seizure susceptibility loci in mice

Seizure susceptibility varies among inbred mouse strains. Chromosome substitution strains (CSS), in which a single chromosome from one inbred strain (donor) has been transferred onto a second strain (host) by repeated backcrossing, may be used to identify quantitative trait loci (QTLs) that contribu...

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Bibliografiska uppgifter
Huvudupphovsmän: Winawer, Melodie R., Kuperman, Rachel, Niethammer, Martin, Sherman, Steven, Rabinowitz, Daniel, Guell, Irene Plana, Ponder, Christine A., Palmer, Abraham A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640942/
https://ncbi.nlm.nih.gov/pubmed/17242861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-006-0087-6
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