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Two Quantitative Trait Loci for Prepulse Inhibition of Startle Identified on Mouse Chromosome 16 Using Chromosome Substitution Strains

Prepulse inhibition (PPI) of acoustic startle is a genetically complex quantitative phenotype of considerable medical interest due to its impairment in psychiatric disorders such as schizophrenia. To identify quantitative trait loci (QTL) involved in mouse PPI, we studied mouse chromosome substituti...

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Detalhes bibliográficos
Main Authors: Petryshen, Tracey L., Kirby, Andrew, Hammer, Ronald P., Purcell, Shaun, O'Leary, Sinead B., Singer, Jonathan B., Hill, Annie E., Nadeau, Joseph H., Daly, Mark J., Sklar, Pamela
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2005 by the Genetics Society of America 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456091/
https://ncbi.nlm.nih.gov/pubmed/15998716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.045658
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