High doses of purified influenza A virus hemagglutinin significantly augment serum and nasal secretion antibody responses in healthy young adults.

The reactogenicity and immunogenicity of purified influenza virus hemagglutinin (HA) vaccines administered intramuscularly were evaluated in two placebo-controlled clinical trials. A total of 139 healthy young adults were randomized to receive increasing doses of monovalent influenza A/Taiwan/1/86 (...

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Bibliographic Details
Main Authors: Keitel, W A, Couch, R B, Cate, T R, Hess, K R, Baxter, B, Quarles, J M, Atmar, R L, Six, H R
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC264085/
https://ncbi.nlm.nih.gov/pubmed/7814484
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