Contrasting Effects of Type I Interferon as a Mucosal Adjuvant for Influenza Vaccine in Mice and Humans

To identify an adjuvant that enhances antibody responses in respiratory secretions to inactivated influenza virus vaccine (IVV), a comparison was made of responses to intranasal vaccinations of mice with IVV containing monophosphoryl lipid A (MPL), type I interferon (IFN) or cholera toxin B (CTB). A...

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Autores principales: Couch, Robert B., Atmar, Robert L., Cate, Thomas R., Quarles, John M., Keitel, Wendy A., Arden, Nancy H., Wells, Janet, Niño, Diane, Wyde, Philip R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778204/
https://ncbi.nlm.nih.gov/pubmed/19607949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.06.084
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