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Yersinia pestis evades TLR4-dependent induction of IL12(p40)(2) by dendritic cells and subsequent cell migration
At the temperature of its flea-vector (~20–30°C) the causative agent of plague, Yersinia pestis, expresses a profile of genes distinct from those expressed in a mammalian host (37°C). When DC are exposed to Y. pestis grown at 26°C (Y. pestis-26°), they secrete copious amounts of IL-12p40 homodimer (...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2640496/ https://ncbi.nlm.nih.gov/pubmed/18832714 |
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