Specificity Protein 1-dependent p53-mediated Suppression of Human Manganese Superoxide Dismutase Gene Expression

Manganese superoxide dismutase (MnSOD) is a primary antioxidant enzyme necessary for the survival of aerobic life. Previously, we demonstrated that specificity protein 1 (Sp1) is essential for the basal transcription of the MnSOD gene. We also identified nucleophosmin (NPM), an RNA-binding protein,...

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Hlavní autoři: Dhar, Sanjit Kumar, Xu, Yong, Chen, Yumin, St. Clair, Daret K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640468/
https://ncbi.nlm.nih.gov/pubmed/16740634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M601083200
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