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Large-scale inference of the point mutational spectrum in human segmental duplications

BACKGROUND: Recent segmental duplications are relatively large (≥ 1 kb) genomic regions of high sequence identity (≥ 90%). They cover approximately 4–5% of the human genome and play important roles in gene evolution and genomic disease. The DNA sequence differences between copies of a segmental dupl...

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Autors principals: Nakken, Sigve, Rødland, Einar A, Rognes, Torbjørn, Hovig, Eivind
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640414/
https://ncbi.nlm.nih.gov/pubmed/19161616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-43
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