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Peptide length significantly influences in vitro affinity for MHC class II molecules

BACKGROUND: Class II Major Histocompatibility Complex (MHC) molecules have an open-ended binding groove which can accommodate peptides of varying lengths. Several studies have demonstrated that peptide flanking residues (PFRs) which lie outside the core binding groove can influence peptide binding a...

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Detalhes bibliográficos
Main Authors: O'Brien, Cathal, Flower, Darren R, Feighery, Conleth
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640366/
https://ncbi.nlm.nih.gov/pubmed/19036163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-7580-4-6
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