HMG I(Y) interferes with the DNA binding of NF-AT factors and the induction of the interleukin 4 promoter in T cells

HMG I(Y) proteins bind to double-stranded A+T oligonucleotides longer than three base pairs. Such motifs form part of numerous NF-AT-binding sites of lymphokine promoters, including the interleukin 4 (IL-4) promoter. NF-AT factors share short homologous peptide sequences in their DNA-binding domain...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Klein-Hessling, Stefan, Schneider, Günter, Heinfling, Annette, Chuvpilo, Sergei, Serfling, Edgar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences of the USA 1996
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC26401/
https://ncbi.nlm.nih.gov/pubmed/8986808
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