Safety and Immunologic Response of a Viral Vaccine to PSA in Combination with Radiation Therapy when Metronomic-Dose IL-2 Is Used as an Adjuvant

PURPOSE: We have previously reported on the safety and immunological response of a poxvirus-based vaccine encoding PSA used in combination with radiation therapy in patients with localized prostate cancer. We hypothesized that a “metronomic” dose of IL-2 as a biologic adjuvant would cause less toxic...

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Main Authors: Lechleider, Robert J., Arlen, Philip M., Tsang, Kwong-Yok, Steinberg, Seth M., Yokokawa, Junko, Cereda, Vittore, Camphausen, Kevin, Schlom, Jeffrey, Dahut, William L., Gulley, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639763/
https://ncbi.nlm.nih.gov/pubmed/18698048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-5162
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