Berberine suppresses MEK/ERK-dependent Egr-1 signaling pathway and inhibits vascular smooth muscle cell regrowth after in vitro mechanical injury

Vascular smooth muscle cell (SMC) proliferation plays an important role in the pathogenesis of atherosclerosis and post-angioplasty restenosis. Berberine is a well-known component of the Chinese herb medicine Huanglian (Coptis chinensis), and is capable of inhibiting SMC contraction and proliferatio...

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Main Authors: Liang, Kae-Woei, Ting, Chih-Tai, Yin, Sui-Chu, Chen, Ying-Tsung, Lin, Shing-Jong, Liao, James K., Hsu, Shih-Lan
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639653/
https://ncbi.nlm.nih.gov/pubmed/16448624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2005.12.028
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