Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for molecules associated with metabolism, signaling and regulation in central nervous system mixed glial cell cultures

BACKGROUND: Cytokines secreted by immune cells and activated glia play central roles in both the pathogenesis of and protection from damage to the central nervous system (CNS) in multiple sclerosis (MS). METHODS: We have used gene array analysis to identify the initial direct effects of cytokines on...

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Detalhes bibliográficos
Main Authors: Lisak, Robert P, Benjamins, Joyce A, Bealmear, Beverly, Nedelkoska, Liljana, Studzinski, Diane, Retland, Ernest, Yao, Bin, Land, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639549/
https://ncbi.nlm.nih.gov/pubmed/19159481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-6-4
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