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Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for molecules associated with metabolism, signaling and regulation in central nervous system mixed glial cell cultures

BACKGROUND: Cytokines secreted by immune cells and activated glia play central roles in both the pathogenesis of and protection from damage to the central nervous system (CNS) in multiple sclerosis (MS). METHODS: We have used gene array analysis to identify the initial direct effects of cytokines on...

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Detaylı Bibliyografya
Asıl Yazarlar: Lisak, Robert P, Benjamins, Joyce A, Bealmear, Beverly, Nedelkoska, Liljana, Studzinski, Diane, Retland, Ernest, Yao, Bin, Land, Susan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639549/
https://ncbi.nlm.nih.gov/pubmed/19159481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-6-4
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