Development of an Optimized Activatable MMP-14 targeted SPECT Imaging Probe

Matrix Metalloproteinase-14 (MT1-MMP or MMP-14) is a membrane-associated protease implicated in a variety of tissue remodeling processes and a molecular hallmark of select metastatic cancers. The ability to detect MMP-14 in vivo would be useful in studying its role in pathologic processes and may po...

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Autori principali: Watkins, Gregory A., Jones, Ella Fung, Shell, M. Scott, VanBrocklin, Henry F., Pan, Mei-Hsiu, Hanrahan, Stephen M., Feng, Jin Jin, He, Jiang, Sounni, Nor Eddine, Dill, Ken A., Contag, Christopher H., Coussens, Lisa M., Franc, Benjamin L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639212/
https://ncbi.nlm.nih.gov/pubmed/19109023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.11.078
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