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Interactions between the juvenile Batten disease gene, CLN3, and the Notch and JNK signalling pathways
Mutations in the gene CLN3 are responsible for the neurodegenerative disorder juvenile neuronal ceroid lipofuscinosis or Batten disease. CLN3 encodes a multi-spanning and hydrophobic transmembrane protein whose function is unclear. As a consequence, the cell biology that underlies the pathology of t...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2638826/ https://ncbi.nlm.nih.gov/pubmed/19028667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn396 |
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