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Necdin, a Prader–Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development
Prader–Willi syndrome (PWS) is a complex genetic disorder characterized by hyperphagia, obesity and hypogonadotrophic hypogonadism, all highly suggestive of hypothalamic dysfunction. The NDN gene, encoding the MAGE family protein, necdin, maps to the PWS chromosome region and is highly expressed in...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2638776/ https://ncbi.nlm.nih.gov/pubmed/18930956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn344 |
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