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Identification of compounds that potentiate CREB signaling as possible enhancers of long-term memory
Many studies have implicated the cAMP Response Element Binding (CREB) protein signaling pathway in long-term memory. To identify small molecule enhancers of CREB activation of gene expression, we screened ≈73,000 compounds, each at 7–15 concentrations in a quantitative high-throughput screening (qHT...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2638736/ https://ncbi.nlm.nih.gov/pubmed/19196967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813020106 |
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