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Isorhodopsin rather than rhodopsin mediates rod function in RPE65 knock-out mice

The chromophore of visual pigments is 11-cis-retinal and, thus, in its absence, opsin is not photosensitive and no visual function exists. However, in the RPE65 knockout (Rpe65(-/-)) mouse, where synthesis of 11-cis-retinal does not occur, a minimal visual response from rod photoreceptors is obtaine...

詳細記述

保存先:
書誌詳細
主要な著者: Fan, Jie, Rohrer, Baerbel, Moiseyev, Gennadiy, Ma, Jian-xing, Crouch, Rosalie K.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC263870/
https://ncbi.nlm.nih.gov/pubmed/14578454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2234461100
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