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Nickel and the Microbial Toxin, MALP-2, Stimulate Proangiogenic Mediators from Human Lung Fibroblasts via a HIF-1α and COX-2–Mediated Pathway

Hypoxia-inducible factor (HIF-1α) and cyclooxygenase-2 (COX-2) have been implicated in the regulation of inflammatory-like processes that lead to angiogenesis and fibrotic disorders. Here we demonstrate that in human lung fibroblasts (HLFs) treated with mixed exposures to chemical and microbial stim...

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Sonraí Bibleagrafaíochta
Main Authors: Brant, Kelly A., Fabisiak, James P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638645/
https://ncbi.nlm.nih.gov/pubmed/18832182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn208
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