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Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway

Pyrin, the familial Mediterranean fever protein, is found in association with the cytoskeleton in myeloid/monocytic cells and modulates IL-1β processing, NF-κB activation, and apoptosis. These effects are mediated in part through cognate interactions with the adaptor protein ASC, which shares an N-t...

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Bibliografski detalji
Glavni autori: Shoham, Nitza G., Centola, Michael, Mansfield, Elizabeth, Hull, Keith M., Wood, Geryl, Wise, Carol A., Kastner, Daniel L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC263843/
https://ncbi.nlm.nih.gov/pubmed/14595024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2135380100
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