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Functional constraints and frequency of deleterious mutations in noncoding DNA of rodents
Selection against deleterious mutations imposes a mutation load on populations because individuals die or fail to reproduce. In vertebrates, estimates of genomic rates of deleterious mutations in protein-coding genes imply the existence of a substantial mutation load, but many functionally important...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC263826/ https://ncbi.nlm.nih.gov/pubmed/14597721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2233252100 |
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