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Leptin reverses long-term potentiation at hippocampal CA1 synapses
The hormone leptin crosses the blood brain barrier and regulates numerous neuronal functions, including hippocampal synaptic plasticity. Here we show that application of leptin resulted in the reversal of long-term potentiation (LTP) at hippocampal CA1 synapses. The ability of leptin to depotentiate...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2638023/ https://ncbi.nlm.nih.gov/pubmed/19054283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05810.x |
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