Frequent Infection of Cerebellar Granule Cell Neurons by Polyomavirus JC in Progressive Multifocal Leukoencephalopathy

Progressive multifocal leukoencephalopathy (PML) occurs most often in immunosuppressed individuals. The lesions of PML result from astrocyte and oligodendrocyte infection by the polyomavirus JC (JCV); JCV has also been shown to infect and destroy cerebellar granule cell neurons (GCNs) in 2 HIV-posit...

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Bibliografiske detaljer
Main Authors: Wüthrich, Christian, Cheng, Yi Min, Joseph, Jeffrey T., Kesari, Santosh, Beckwith, Curt, Stopa, Edward, Bell, Jeanne E., Koralnik, Igor J.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637912/
https://ncbi.nlm.nih.gov/pubmed/19104450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e3181912570
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