Frequent Infection of Cerebellar Granule Cell Neurons by Polyomavirus JC in Progressive Multifocal Leukoencephalopathy

Progressive multifocal leukoencephalopathy (PML) occurs most often in immunosuppressed individuals. The lesions of PML result from astrocyte and oligodendrocyte infection by the polyomavirus JC (JCV); JCV has also been shown to infect and destroy cerebellar granule cell neurons (GCNs) in 2 HIV-posit...

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Autori principali: Wüthrich, Christian, Cheng, Yi Min, Joseph, Jeffrey T., Kesari, Santosh, Beckwith, Curt, Stopa, Edward, Bell, Jeanne E., Koralnik, Igor J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637912/
https://ncbi.nlm.nih.gov/pubmed/19104450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e3181912570
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