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A Small Subset of Signal Peptidase Residues are Perturbed by Signal Peptide Binding

Perturbations of the chemical shifts of a small subset of residues in the catalytically active domain of Escherichia coli signal peptidase I (SPase I) upon binding signal peptide suggest the contact surface on the enzyme for the substrate. SPase I, an integral membrane protein, is vital to preprotei...

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Main Authors: Musial-Siwek, Monika, Yeagle, Philip L., Kendall, Debra A.
格式: Artigo
語言:Inglês
出版: 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637466/
https://ncbi.nlm.nih.gov/pubmed/18637988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2008.00685.x
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