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Sgt1, a co-chaperone of Hsp90 stabilizes Polo and is required for centrosome organization
Sgt1 was described previously in yeast and humans to be a Hsp90 co-chaperone and required for kinetochore assembly. We have identified a mutant allele of Sgt1 in Drosophila and characterized its function. Mutations in sgt1 do not affect overall kinetochore assembly or spindle assembly checkpoint. sg...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637337/ https://ncbi.nlm.nih.gov/pubmed/19131964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.283 |
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